Already at the age of 20, Miroslav Drofa, a graduate of the Higher School of Building Industry in Pilsen (1923-1927), began working as a builder and budgeter (assistant and draughtsman) in the building department of the T. & A. Bata company in Zlín (1928). Thanks to regular contact with the leading Bata architects František Lýdia Gahura, Vladimír Karfík and Jiří Voženílek, he developed into a leading representative of Zlín's functionalist architecture. From the firm's perspective, he ideally combined the disposition of a building economist and a designer, reducing construction costs while maintaining a higher standard of living. From 1932 he participated in the design of Bata factory towns in Czechoslovakia and abroad.

Drofa's first major independent project was the standard single-family house with a garage "Drofa" (1937). However, his most important task after 1939 was in charge of the design construction department of the Bata company in Zruč nad Sázavou - Bata. Together with V. Karfík, he implemented the designs of the factory building No. 2, the municipal school, the Social House, the liberty houses I-III and the company housing estate. In 1942, he was called back to Zlín and placed at the head of the housing construction department, where he participated in the projects of the Bata satellites in Otrokovice-Batau, Napajedle and the Slovak Batovany.

After 1945, M. Drofa, in the Stavosvit and Centroprojekt organisations, was significantly involved in the construction reconstruction of Zlín, which had been damaged by the bombing. In addition to housing construction (1947 experimental Zlín housing estate Podvesná), Drofa was involved in industrial construction and projects of production complexes in which he foresaw the growing influence of production automation and its impact on the spatial organisation of production (Jitex Písek, Slovenka Banská Bystrica, Jablonex Jablonec nad Nisou, Tatrasvit Košice, Vozovna Ostrava-Poruba, etc.).

Although most of Drofa's more than a hundred projects were created under the pressure of changing economic or ideological dictates, Drofa never lost his own handwriting as a creator of purposeful buildings without ambitions to build monuments to his fame with his own buildings. The architect M. Drofa was buried in the Forest Cemetery in Zlín.

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